Issues of Substance (IOS) is the premier educational event in Canada for the substance abuse field. Organized by the Canadian Centre on Substance Abuse in partnership with the Canadian Executive Council on Addictions (CECA), IOS is an important knowledge exchange, research and networking opportunity for professionals in the field. The theme for IOS 2013 is From Knowledge to Know-how: Learn, Inspire, Change. IOS participants will learn new skills and explore knowledge to help inform practice and policy development through a series of workshops, exhibits and presentations.